The simple answer to this is yes with the right design. You don’t have to use furniture specifically designed for RVs. In fact, most RV office ideas I’ve seen utilize standard furniture. This doesn’t mean to go for that solid maple executive desk, but a trip to your local Ikea or Home Depot might be in order.
Think repurpose or unique utilization while you are at it. I once came across a built-in work area that was made from a shelf and three sets of storage cubes as the base.